glutathione metabolism in red blood cells system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis Mechanisms tagging senescent red blood

At indicated times after washout, CMFDA (500 nM) was added for 1 h and the cells were lysed and processed for in-gel fluorescence binding assay, to assess recovery of CMFDA binding to GSTO1

Rahman I, Kode A, Biswas SK

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Due to the conformational differences between the P72 and R72 missense mutants, we speculated that their propensity for rescue by p53 targeting drugs, such as APR-246, may differ in that mutants with the P72 SNP would exhibit increased sensitivity